発表論文 (Publications)

学術論文(publications)

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2014

• Direct Nucleophilic Difluoromethylation of Aromatic Isoxazoles Activated by Electron-Withdrawing Groups Using (Difluoromethyl)trimethylsilane
  Wang, X.; Tokunaga, E.; Shibata, N. ScienceOpen 2014 [Abstract]
  DOI: 10.14293/S2199-1006.1.SOR-CHEM.AD1QVW.v2
  
  
• Sterically Demanding Unsymmetrical Diaryl-λ³-iodanes for Electrophilic Pentafluorophenylation and an Approach to α-Pentafluorophenyl Carbonyl Compounds with an All-Carbon Stereocenter
  Matsuzaki, K.; Okuyama, K.; Tokunaga, E.; Shiro, M.; Shibata, N.
  ChemistryOpen 2014, 3, 233-237. [Abstract]
  DOI: 10.1002/open.201402045
  
  
• Synthesis and property of novel phthalocyanine having a 3,5-bis-pentafluorosulfanylphenyl group on the α-peripheral position
  Iida, N.; Tokunaga, E.; Saito, N.; Shibata, N.
  J. Fluorine Chem. 2014, 168, 93-98. [Abstract]
  DOI: 10.1016/j.jfluchem.2014.09.012
  
  
• Synthesis and optical properties of trifluoroethoxy-substituted double-decker phthalocyanines
  Mori, S.; Ogawa, N.; Tokunaga, E.; Shibata, N.
  J. Porphyrins Phthalocyanines 2014, 18, 1034-1041. [Abstract]
  DOI: 10.1142/S1088424614500862
  
  
• An aza-Michael Addition Protocol to Fluoroalkylated β-Amino Acids Derivatives and Enantiopure Trifluoromethylated N-Heterocycles
  Yang, X.; Chen, Z.; Cai, Y.; Huang, Y.-Y.; Shibata, N.
  Green Chem. 2014, 16, 4530-4534. [Abstract]
  DOI: 10.1039/C4GC01357C
  
  
• Studies on the C/O-regioselectivity in Electrophilic Fluoromethylations of β-Ketoesters based on Thermodynamics by Ab initio Calculations
  Yang, Y.-D.; Wang, X.; Tsuzuki, S.; Tokunaga, E.; Shibata, N.
  Bull. Korean Chem. Soc. 2014, 35, 1851-1854. [Abstract]
  DOI: 10.5012/bkcs.2014.35.6.1851
  
  
• Asymmetric Synthesis of Efavirenz via Organocatalyzed Enantioselective Trifluoromethylation
  Okusu, S.; Kawai, H.; Yasuda, Y.; Sugita, Y.; Kitayama, T.; Tokunaga, E.; Shibata, N.
  Asian J. Org. Chem. 2014, 35, 449-452. [Abstract]
  DOI: 10.1002/ajoc.201402016
  
  
• Iodoarene-catalyzed fluorination and aminofluorination by an Ar-I/HF・pyridine/mCPBA system
  Suzuki, S.; Kamo, T.; Fukushi, K.; Hiramatsu, T.; Tokunaga, T.; Dohi, T.; Kita Y.; Shibata N.
  Chem. Sci. 2014, 5, 2754-2760. [Abstract]
  DOI: 10.1039/C3SC53107D
  
  
• Bis(pentafluorosulfanyl)phenyl Azide as an Expeditious Tool for Click Chemistry toward Antitumor Pharmaceuticals
  Yang, Y.-D.; Tokunaga, E.; Akiyama, H.; Saito, N.; Shibata, N.
  ChemMedChem 2014, 9, 913-917. [Abstract]
  DOI: 10.1002/cmdc.201400059
  
  
• Diastereoselective Additive Trifluoromethylation/Halogenation of Isoxazole Triflones: Synthesis of All-Carbon-Functionalized Trifluoromethyl Isoxazoline Triflones
  Kawai, H.; Sugita, Y.; Tokunaga, E.; Sato, H.; Shiro, M.; Shibata, N.
  ChemistryOpen 2014, 3, 14-18. [Abstract]
  DOI: 10.1002/open.201300044
  
  
• A phthalocyanine-subphthalocyanine heterodinuclear dimer: comparison of spectroscopic properties with those of homodinuclear dimers of constituting unitss
  Shibata, N.; Mori, S.; Hayashi, M.; Umeda, M.; Tokunaga, E.; Shiro, M.; Sato, H.;Hoshi, T.; Kobayashi, N.
  Chem. Commun. 2014, 50, 3040-3043. [Abstract]
  DOI: 10.1039/C3CC49831J
  
  
• Thalidomide Increases Human Hepatic Cytochrome P450 3A Enzymes by Direct Activation of the Pregnane X Receptor
  Murayama, N.; van Beuningen, R.; Suemizu, H.; Guguen-Guillouzo, C.; Shibata, N.; Yajima, K.; Utoh, M.; Shimizu, M.; Chesne, C.; Nakamura, M.; Guengerich, F. P.; Houtman, R.; Yamazaki, H.
  Chem. Res. Toxicol. 2014, 27, 304-308. [Abstract]
  DOI: 10.1021/tx4004374
  
• S-((Phenylsulfonyl)difluoromethyl)thiophenium Salts: Carbon-Selective Electrophilic Difluoromethylation of β-Ketoesters, β-Diketones, and Dicyanoalkylidenes
  Wang, X.; Liu, G.; Xu,X.-H.; Shibata, N.; Tokunaga, E.; Shibata, N.
  Angew. Chem. Int. Ed. 2014, 53, 1827-1831. [Abstract]
  DOI: 10.1002/anie.201309875
  
  
• Asymmetric Mannich reaction between (S)-N-(tert-butanesulfinyl)-3,3,3-trifluoroacetaldimine and malonic acid derivatives. Stereodivergent synthesis of (R)- and (S)-3-amino-4,4,4-trifluorobutanoic acids
  Shibata, N.; Nishimine, T.; Shibata, N.; Tokunaga, E.; Kawada, K.; Kagawa, T.; Acena, J. L.; Sorochinsky, A. E.; Soloshonok, V. A.
  Org. Biomol. Chem. 2014, 12, 1454-1462. [Abstract]
  DOI: 10.1039/C3OB42425A
  
  
• NH-type of chiral Ni(II) complexes of glycine Schiff base: design, structural evaluation, reactivity and synthetic applications
  Bergagnini, M.; Fukushi, K.; Han, J.; Shibata, N.; Roussel, C.; Ellis, T. K.; Acenae, J. L.; Soloshonok, V. A.
  Org. Biomol. Chem. 2014, 12, 1278-1291. [Abstract]
  DOI: 10.1039/C3OB41959B
  
• Human Cytochrome P450 Oxidation of 5-Hydroxythalidomide and Pomalidomide, an Amino Analogue of Thalidomide
  Chowdhury, G.; Shibata, N.; Yamazaki, H.; Guengerich, F. P.
  Chem. Res. Toxicol. 2014, 27, 147-156. [Abstract]
  DOI: 10.1021/tx4004215
  
• Kinetic Resolution of Allyl Fluorides by Enantioselective Allylic Trifluoromethylation Based on Silicon-Assisted C-F Bond Cleavage
  Nishimine, T.; Fukushi, K.; Shibata, N.; Taira, H.; Tokunaga, E.; Yamano, A.; Shiro, M.; Shibata, N.
  Angew. Chem. Int. Ed. 2014, 53, 517-520. [Abstract]
  DOI: 10.1002/anie.201308071
  Inside Coverに採択されました。