Dewa・Kondo Lab.
Professor Takehisa DEWA
Department of Life Science and Applied Chemistry
Graduate School of Engineering
Nagoya Institute of Technology
Room320,Bidg19
Gokiso-cho, Showa, Nagoya,466-8555 Japan
takedewa*nitech.ac.jp(*=@)
Phone:+81-52-735-5144｜Web
Affiliation
Department of Life Science and Applied Chemistry
Academic Degree
Doctor of Engineering (Tokyo Institute of Technology, 1994)
Academic background
| 1994 | Department of Polymer Chemistry, Graduate School of Engineering, Tokyo Institute of Technology |
| 1994–1996 | Postdoctoral fellow, Lehigh University, USA (Professor Steven L. Regen) |
| 1996–2000 | Postdoctoral fellow, Kyushu University, Japan (CREST/JST, Professor Yasuhiro Aoyama) |
| 2001–2004 | Assistant Professor, Nagoya Institute of Technology |
| 2001–2005 | PRESTO Researcher (Organization and Function, JST) |
| 2004–2008 | Lecturer, Nagoya Institute of Technology |
| 2008–2016 | Associate Professor, Nagoya Institute of Technology |
| 2009-2013 | PRESTO Researcher (Chemical Conversion of Light Energy, JST) |
| 2016-present | Professor, Nagoya Institute of Technology |
Research Interests
- Structure and function of biomolecular assemblies
- Construction and functional analysis of photosynthetic antenna systems
- Drug delivery systems using synthetic lipids
Membership
American Chemical Society, The Chemical Society of Japan, The Society of Polymer Science,
The Biophysical Society of Japan, The Japanese Society of Photosunthesis Research
Selected Publications(2010-Present)
- Oxygen-Evolving Porous Glass Plates Containing the Photosynthetic Photosystem II Pigment-Protein Complex
T. Noji, K. Kawakami, J. R. Shen, T. Dewa, M. Nango, N. Kamiya, S. Itoh, T. Jin
Langmuir, 32, 7796–7805, 2016. - Light-induced hydrogen production by Photosystem I–Pt nanoparticle conjugates immobilized in porous glass plate nanopores
T. Noji, T. Suzuki, M. Kondo, T. Jin, K. Kawakami, T. Mizuno, H. Oh-oka, M. Ikeuchi, M. Nango, Y. Amao, N. Kamiya, T. Dewa
Res. Chem. Intermed. 42 (11) 7731-7742 (2016) - One-step encapsulation of siRNA between lipid-layers of multi-layer polycation liposomes by lipoplex freeze-thawing
H. Koide, A. Okamoto, H. Tsuchida, H. Ando, S. Ariizumi, C. Kiyokawa, M. Hashimoto, T. Asai, T. Dewa, N. Oku
J. Controlled Release 228, 1-8 2016 - Extension of Light-Harvesting Ability of Photosynthetic Light-Harvesting Complex 2 (LH2) through Ultrafast Energy Transfer from Covalently Attached Artificial Chromophores
Y. Yoneda, T. Noji, T. Katayama, N. Mizutani, D. Komori, M. Nango, H. Miyasaka, S. Itoh, Y. Nagasawa, T. Dewa
J. Am. Chem. Soc., 137, 13121-13129 (2015) - Advanced cancer therapy by integrative antitumor actions via systemic administration of miR-499
H. Ando, T. Asai, H. Koide, A. Okamoto, N. iMaeda, K. Tomita, T. Dewa, T. Minamino, N. Oku
J. Controlled Release 181, 32-39 (2014) - Light-driven Hydrogen Production by Hydrogenases and a Ru-complex inside a Nanoporous Glass Plate under Aerobic External Conditions
T. Noji, M. Kondo, T. Jin, T. Yazawa, H. Osuka, Y. Higuchi, M. Nango, S. Itoh, T. Dewa
J. Phys. Chem. Lett. 5, 2402–2407 (2014) - Gating-Associated Clustering−Dispersion Dynamics of the KcsA Potassium Channel in a Lipid Membrane
A. Sumino, D. Yamamoto, M. Iwamoto, T. Dewa, S. Oiki
J. Phys. Chem. Lett. 5, 578-584 (2014) - Structure–Function Relationships of the Supramolecular Assembly of the Bacterial Photosynthetic Antenna Complexes in Lipid Membranes
T. Dewa, A. Sumino, N. Watanabe, T. Noji, M. Nango
Res. Chem. Intermed. 40, 3243-3256 (2014) - Influence of Phospholipid Composition on Self-Assembly and Energy-Transfer Efficiency in Networks of Light-Harvesting 2 Complexes
A. Sumino, T. Dewa, T. Noji, Y. Nakano, N. Watanabe, R. Hildner, N. Bösch, J. Köhler, M. Nango
J. Phys. Chem. B 117, 10395–10404 (2013) - Electron Conduction and Photocurrent Generation of a Light-Harvesting/Reaction Center Core Complex in Lipid Membrane Environments
A. Sumino, T. Dewa, N. Sasaki, M. Kondo, M. Nango
J. Phys. Chem. Lett. 4, 1087–1092 (2013) - Energy Transfer and Clustering of Photosynthetic Light-Harvesting Complexes in Reconstituted Lipid Membranes
T. Dewa, A. Sumino, N. Watanabe, T. Noji, M. Nango
Chem. Phys., 419, 200-204 (2013) - The Open Gate Structure of the Membrane-Embedded KcsA Potassium Channel Viewed From the Cytoplasmic Side
A. Sumino, T. Sumikama, M. Iwamoto, T. Dewa, S. Oiki
Scientific Reports 3, 1063 (2013) - Immobilization and Photocurrent Activity of a Light-Harvesting Antenna Complex II, LHCII Isolated from a Plant on Electrodes
M. Nagata, M. Amano, T. Joke, K. Fuji, A. Okuda, M. Kondo, S. Ishigure, T. Dewa, K. Iida, F. Secundo, Y. Amao, H. Hashimoto, M. Nango
ACS Macro Lett., 1, 296-299 (2012) - RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment
N. Yonenaga, E. Kenjo, T. Asai, A. Tsuruta, K. Shimizu, T. Dewa, M. Nango, N. Oku
J. Control. Release 160, 177-181 (2012) - Construction and Structural Analysis of Tethered Lipid Bilayer Containing Photosynthetic Antenna Proteins for Functional Analysis
A. Sumino, T. Dewa, T. Takeuchi, R. Sugiura, N. Sasaki, N. Misawa, R. Tero, T. Urisu, A. T. Gardiner, R. J. Cogdell, H. Hashimoto, M. Nango
Biomacromolecules, 12, 2850-2858 (2011) - Dicetyl phosphate-tetraethylenepentamine-based Liposomes for Systemic siRNA Delivery
T. Asai, S. Matsushita, E. Kenjo, T. Tsuzuku, N. Yonenaga, H. Koide, K. Hatanaka, T. Dewa, M. Nango, N. Maeda, H. Kikuchi, N. Oku
Bioconjugate Chem. 22 429-435 (2011) - Reconstitution and AFM Observation of Photosynthetic Membrane Protein Assembly in Planar Lipid Bilayers
A. Sumino, T. Dewa, N. Sasaki, N. Watanabe, M. Kondo, T. Morii, H. Hashimoto, M. Nango
e-J. Surf. Sci. Nanotech. 9, 15-20 (2011) (Editor’s choice) - Selective Assembly of Photosynthetic Antenna Proteins into a Domain-Structured Lipid Bilayer for the Construction of Artificial Photosynthetic Antenna Systems: Structural Analysis of the Assembly using Surface Plasmon Resonance and Atomic Force Microscopy
A. Sumino, T. Dewa, M. Kondo, T. Morii, H. Hashimoto, A. T. Gardiner, R. J. Cogdell, M. Nango
Langmuir, 27, 1092-1099 (2011) - Liposomal Polyamine–Dialkyl Phosphate Conjugates as Effective Gene Carriers: Chemical Structure, Morphology, and Gene Transfer activity
T. Dewa, T. Asai, Y. Tsunoda, K. Kato, D. Baba, M. Uchida, A. Sumino, K. Niwata, T. Umemoto, K. Iida, N. Oku, M. Nango
Bioconjugate Chem., 21, 844-852 (2010)
