出羽・近藤研究室
教授/Professor 出羽 毅久 / Takehisa DEWA
国立大学法人 名古屋工業大学
生命・応用化学科/専攻
共同ナノメディシン科学専攻
〒466-8555 名古屋市昭和区御器所町
takedewa*nitech.ac.jp(*=@)
Phone:052-735-5144｜Web
所属
生命・応用化学専攻（生命・物質科学分野）
共同ナノメディシン科学専攻
略歴
| 平成6年 | 東京工業大学理工学研究科博士後期課程（高分子工学専攻）修了 博士（工学） |
| 平成6年 | 米国Lehigh University 博士研究員 (Professor Steven L. Regen) |
| 平成8年 | 科学技術振興事業団CREST研究員（九州大学 青山安宏 教授） |
| 平成13年 | 名古屋工業大学工学部応用化学科 助手 |
| 平成13年 | 科学技術振興事業団 戦略的創造研究さきがけ21研究員（｢組織化と機能｣領域）兼任 |
| 平成15年 | 名古屋工業大学大学院工学研究科 講師 |
| 平成20年 | 名古屋工業大学大学院工学研究科 未来材料創成工学専攻 准教授 |
| 平成21年 | 科学技術振興機構さきがけ研究員（｢光エネルギーと物質変換｣領域）兼任 |
| 平成28年 | 名古屋工業大学大学院 生命・応用化学専攻/共同ナノメディシン科学専攻 教授 |
研究テーマ
生体分子の集合構造と機能相関
- 光合成膜タンパク質の集合構造ー機能相関
- 光合成膜タンパク質の人工系への応用
- ポリアミン脂質を用いた核酸デリバリーシステム
主要論文(2010-現在）
名工大・研究者詳細（別ページが開きます）
- Oxygen-Evolving Porous Glass Plates Containing the Photosynthetic Photosystem II Pigment-Protein Complex
T. Noji, K. Kawakami, J. R. Shen, T. Dewa, M. Nango, N. Kamiya, S. Itoh, T. Jin
Langmuir, 32, 7796–7805, 2016. - Light-induced hydrogen production by Photosystem I–Pt nanoparticle conjugates immobilized in porous glass plate nanopores
T. Noji, T. Suzuki, M. Kondo, T. Jin, K. Kawakami, T. Mizuno, H. Oh-oka, M. Ikeuchi, M. Nango, Y. Amao, N. Kamiya, T. Dewa
Res. Chem. Intermed. 42 (11) 7731-7742 (2016) - One-step encapsulation of siRNA between lipid-layers of multi-layer polycation liposomes by lipoplex freeze-thawing
H. Koide, A. Okamoto, H. Tsuchida, H. Ando, S. Ariizumi, C. Kiyokawa, M. Hashimoto, T. Asai, T. Dewa, N. Oku
J. Controlled Release 228, 1-8 2016 - Extension of Light-Harvesting Ability of Photosynthetic Light-Harvesting Complex 2 (LH2) through Ultrafast Energy Transfer from Covalently Attached Artificial Chromophores
Y. Yoneda, T. Noji, T. Katayama, N. Mizutani, D. Komori, M. Nango, H. Miyasaka, S. Itoh, Y. Nagasawa, T. Dewa
J. Am. Chem. Soc., 137, 13121-13129 (2015) - Advanced cancer therapy by integrative antitumor actions via systemic administration of miR-499
H. Ando, T. Asai, H. Koide, A. Okamoto, N. iMaeda, K. Tomita, T. Dewa, T. Minamino, N. Oku
J. Controlled Release 181, 32-39 (2014) - Light-driven Hydrogen Production by Hydrogenases and a Ru-complex inside a Nanoporous Glass Plate under Aerobic External Conditions
T. Noji, M. Kondo, T. Jin, T. Yazawa, H. Osuka, Y. Higuchi, M. Nango, S. Itoh, T. Dewa
J. Phys. Chem. Lett. 5, 2402–2407 (2014) - Gating-Associated Clustering−Dispersion Dynamics of the KcsA Potassium Channel in a Lipid Membrane
A. Sumino, D. Yamamoto, M. Iwamoto, T. Dewa, S. Oiki
J. Phys. Chem. Lett. 5, 578-584 (2014) - Structure–Function Relationships of the Supramolecular Assembly of the Bacterial Photosynthetic Antenna Complexes in Lipid Membranes
T. Dewa, A. Sumino, N. Watanabe, T. Noji, M. Nango
Res. Chem. Intermed. 40, 3243-3256 (2014) - Influence of Phospholipid Composition on Self-Assembly and Energy-Transfer Efficiency in Networks of Light-Harvesting 2 Complexes
A. Sumino, T. Dewa, T. Noji, Y. Nakano, N. Watanabe, R. Hildner, N. Bösch, J. Köhler, M. Nango
J. Phys. Chem. B 117, 10395–10404 (2013) - Electron Conduction and Photocurrent Generation of a Light-Harvesting/Reaction Center Core Complex in Lipid Membrane Environments
A. Sumino, T. Dewa, N. Sasaki, M. Kondo, M. Nango
J. Phys. Chem. Lett. 4, 1087–1092 (2013) - Energy Transfer and Clustering of Photosynthetic Light-Harvesting Complexes in Reconstituted Lipid Membranes
T. Dewa, A. Sumino, N. Watanabe, T. Noji, M. Nango
Chem. Phys., 419, 200-204 (2013) - The Open Gate Structure of the Membrane-Embedded KcsA Potassium Channel Viewed From the Cytoplasmic Side
A. Sumino, T. Sumikama, M. Iwamoto, T. Dewa, S. Oiki
Scientific Reports 3, 1063 (2013) - Immobilization and Photocurrent Activity of a Light-Harvesting Antenna Complex II, LHCII Isolated from a Plant on Electrodes
M. Nagata, M. Amano, T. Joke, K. Fuji, A. Okuda, M. Kondo, S. Ishigure, T. Dewa, K. Iida, F. Secundo, Y. Amao, H. Hashimoto, M. Nango
ACS Macro Lett., 1, 296-299 (2012) - RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment
N. Yonenaga, E. Kenjo, T. Asai, A. Tsuruta, K. Shimizu, T. Dewa, M. Nango, N. Oku
J. Control. Release 160, 177-181 (2012) - Construction and Structural Analysis of Tethered Lipid Bilayer Containing Photosynthetic Antenna Proteins for Functional Analysis
A. Sumino, T. Dewa, T. Takeuchi, R. Sugiura, N. Sasaki, N. Misawa, R. Tero, T. Urisu, A. T. Gardiner, R. J. Cogdell, H. Hashimoto, M. Nango
Biomacromolecules, 12, 2850-2858 (2011) - Dicetyl phosphate-tetraethylenepentamine-based Liposomes for Systemic siRNA Delivery
T. Asai, S. Matsushita, E. Kenjo, T. Tsuzuku, N. Yonenaga, H. Koide, K. Hatanaka, T. Dewa, M. Nango, N. Maeda, H. Kikuchi, N. Oku
Bioconjugate Chem. 22 429-435 (2011) - Reconstitution and AFM Observation of Photosynthetic Membrane Protein Assembly in Planar Lipid Bilayers
A. Sumino, T. Dewa, N. Sasaki, N. Watanabe, M. Kondo, T. Morii, H. Hashimoto, M. Nango
e-J. Surf. Sci. Nanotech. 9, 15-20 (2011) (Editor’s choice) - Selective Assembly of Photosynthetic Antenna Proteins into a Domain-Structured Lipid Bilayer for the Construction of Artificial Photosynthetic Antenna Systems: Structural Analysis of the Assembly using Surface Plasmon Resonance and Atomic Force Microscopy
A. Sumino, T. Dewa, M. Kondo, T. Morii, H. Hashimoto, A. T. Gardiner, R. J. Cogdell, M. Nango
Langmuir, 27, 1092-1099 (2011) - Liposomal Polyamine–Dialkyl Phosphate Conjugates as Effective Gene Carriers: Chemical Structure, Morphology, and Gene Transfer activity
T. Dewa, T. Asai, Y. Tsunoda, K. Kato, D. Baba, M. Uchida, A. Sumino, K. Niwata, T. Umemoto, K. Iida, N. Oku, M. Nango
Bioconjugate Chem., 21, 844-852 (2010)
