論文(2002~)

●2002年度

①:Cytotoxic Activity of Physalins Possessing Modified Skeletal Structures against HeLa Cells
   Makino, B.; Ohya, J.; Yamamura, H.; Araki, S.; Butsugan, Y.; Kawai, M.
   Parmazie, 57, 70-71 (2002.1)


②:Tautomerism between Exomethylene Type Physalins and Oxymethylene-bridged Physalins
   Makino, B.; Kawai, M.; Yamamura, H.; Araki, B.; Butsugan, Y.
   Pharmazie, 57, 215-216 (2002.3)


③:Cytotoxic Activity of Physalins and Related Compounds against HeLa Cells
   Kawai, M.; Makino, B.; Yamamura, H.; Araki, S.; Butsugan, Y.; Ohya ,J
   Pharmazie, 57, 348-350 (2002.5)


④:Stereochemistry of Protected Ornithine Side Chains of Gramicidin S Derivatives:X-ray Crystal Structure of the Bis-Boc-tetra-N-methyl Derivative of Gramicidin S
   Yamada, K.; Unno, M.; Kobayashi, K.; Oku, H.; Yamamura, H.; Araki, S.;Matsumoto, H.; Katakai, R.; Kawai, M.
   J.Am. Chem. Soc.,124, 12684-12686 (2002.10)

●2003年度

①:reparation of Hexakis(6-O-mesitylsulfonyl)cyclomaltooctaoses and Structural Validation of
   the Four Isomers Using Heteronuclear Multiple Bond Correlation Spectroscopy
   Yamamura, H.; Miyachi, S.; Kano, K.; Araki, S.; Lee, K.; Kawai, M.;Ueyama, N.
   Bull. Chem. Soc. Jpn., 76, 171-175 (2003.1)


②:Preparation of β-Cyclodextrin Derivatives Possessing Two Trimethylammonio Groups on Their Primary Hydroxy Sides as Chiral Selectors
   Yamamura , H.; Yamada, Y.; Miyagi, R.; Kano, K.; Araki, S.; Kawai, M.
   J. Incl. Phenom. Macrocycl. Chem., 45, 211-216 (2003.4)


③:Complexation and Chiral Recognition Thermodynamics of β-Cyclodextrin with N-Acetyl- and N-Carbobenzyloxy-dipetides Possessing Two Aromatic Rings
   Rekharsky, M. V.; Yamamura, H.; Kawai, M.; Inoue, Y.
   J. Org. Chem., 13, 5228-5235 (2003.6)


④:Extra Amino Group-containing Gramicidin S Analogs Possessing Outer Membrane-permeabilizing Activity.
   Kawai, M.; Tanaka, R.; Yamamura, H.; Yasuda, K.; Narita, S.; Umemoto,H.; Ando, S.; Katsu, T.
   Chem. Commun., 1264-1265 (2003.6)


⑤:Crystal Structures of Protected Derivatives of Alkoxyglycines
   Kawai, M.; Hosoda, K.; Omori, Y.; Yamamura, H.; Miwa, Y.; Taga, T.
   Bull. Chem. Soc. Jpn., 76, 2215-2216 (2003.11)

●2004年度

①:Factors Controlling the Complex Architecture of Native and Modified Cyclodextrins with Dipeptide (Z-Glu-Tyr) Studied
   by Microcalorimetry and NMR Spectroscopy: Critical Effects of Peripheral Bis-trimethylamination and Cavity Size.
   Yamamura, H.; Rekharsky, M. V.; Ishihara, Y.; Kawai, M.; Inoue, Y.
   J. Am. Chem. Soc., 126, 14224-14233 (2004.11)

●2005年度

①:Proline Residue-modified Polycationic Analogs of Gramicidin S with High Antibacterial Activity against Both Gram-positive and Gram-negative Bacteria and Low Hemolytic Activity
   Kawai, M.; Yamamura, H.; Tanaka, R.; Umemoto, H.; Ohmizo, C.; Higuchi,S.; Katsu, T.
   J. Peptide Res., 65, 98-104 (2005.1)

●2006年度

①:Sequential Formation of a Ternary Complex among Dihexylammonium, Cucurbit[6]uril, and Cyclodextrin with Positive Cooperativity
   Rekharsky, M. V.; Yamamura, H.; Kawai, M.; Osaka, I.; Arakawa, R.; Sato,A.; Ho Ko, Y.; Selvapalam, N.; Kim, K.; Inoue, Y.
   Org. Lett., 8, 815-818 (2006.3)


②:Electrospray Ionization Tandem Mass Spectrometry Determined Regioisomeric Structures of Disubstituted β-Cyclodextrin Derivative
   Yamamura, H.; Iwata, T.; Kawai, M.; Sato A.
   Eur. J. Mass Spectrom.,12, 37–42 (2006.1)


③:Chiral Recognition in Cucurbituril Cavities
   Rekharsky, M. V.; Yamamura, H.; Inoue, C.; Kawai, M.; Osaka, I. Arakawa, R.; Shiba, K.; Sato, A.; Ho Ko, Y.; Selvapalam,N.; Kim, K.; Inoue, Y.
   J. Am. Chem. Soc., 128, 14871–14880 (2006.11)

●2007年度

①:Poysulfonylated Cyclodextrins. Part 13. Chemistry of Cyclomaltoheptaose
  Tetrasulfonates Providing a Complete 6-O-Sulfonylated CyclomaltoheptaosesLibrary
  Yamamura, H.; Tashiro, H.; Kawasaki, J.; Kawamura, K.; Kawai, M.
  Tetrahedron, 63, 2064–2069 (2007.1)

②:Phosphodiester bond cleavage by dinuclear zinc(II) complex constructed on cyclic and linear peptides.
  Nakazawa, Ryou; Yamamura, Hatsuo; Kawai,
  Masao. Peptide Science (2006), 352-353 (2007)

③:Specific interaction of naturally occurring obesity related peptides   with cucurbit[7]uril macrocycle in aqueous solution.
  Rekharsky, MikhailV.; Yamamura, Hatsuo; Ko, Young Ho; Kim, Kimoon; Inoue, Yoshihisa.
  Peptide Science (2006), 393-394 (2007)

④:Preparation of a Cyclodextrin Dimer Linked with a Bis(picolinyl)cystine   Moiety and Its Intra- and Intermolecular Inclusion Behavior
  Yamamura, H.; Satake, K.; Hirasawa, R.; Yamada, S.; Kawai, M. J.
  Inclusion Phenom. Macrocyclic Chem., 57, 261-264 (2007)

⑤:A Comprehensive b-Cyclodextrin 6-O-Sulfonates Library Providing Nineteen   Sulfonylated Derivatives
  Yamamura, H.
  Proceedings of Fourth Asian Cyclodextrin Conference (ACC2007), 59-64 (2007)

●2008年度

①:a-Aminoisobutyryl-L-prolyl Sequence For Building Dipeptide Molecular   Switching System
  Koike, H.; Yasuda,H.; Mori, F.; Kishikawa, K.; Kawai,M.; Yamamura, H.
  Peptide Science 2007 , 123-124 (2008)